home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9406b.zip
/
M9460239.TXT
< prev
next >
Wrap
Text File
|
1994-06-12
|
3KB
|
40 lines
Document 0239
DOCN M9460239
TI Manifestations of Epstein-Barr virus-associated disorders in liver.
DT 9408
AU Markin RS; Department of Pathology and Microbiology, University of
Nebraska; Medical Center, Omaha 68198-3135.
SO Liver. 1994 Feb;14(1):1-13. Unique Identifier : AIDSLINE MED/94231939
AB Epstein-Barr virus is a ubiquitous virus associated with a variety of
different diseases and disorders. The manifestations of Epstein-Barr
virus-associated diseases or disorders within the liver, which involve a
broad spectrum of histologic and clinical features, ranging from
hepatitis through lymphoproliferative disorders to lymphoma, are
presented. An important aspect of Epstein-Barr virus expression and
infection is the biology of the Epstein-Barr virus. Documentation of
infection can be performed using serology to detect the interaction of
Epstein-Barr virus with the immune system, and the detection of EBV
proteins and use of molecular biologic techniques to identify the
presence of EBV RNA, and DNA sequences. Of particular utility are in
situ hybridization, Southern blot analysis, and polymerase chain
reaction as diagnostic methods to identify specific RNA or DNA
sequences. Epstein-Barr virus-associated diseases and disorders
including infectious mononucleosis, sporadic fatal infectious
mononucleosis, X-linked proliferative disorder (Duncan's disease),
post-transplant lymphoproliferative disorders, lymphoma, and AIDS are
discussed. The histopathologic findings present in liver associated with
each disease are presented with illustrative examples. Handling the
tissue and interaction with clinical services are also discussed as a
method for appropriate diagnosis of Epstein-Barr virus-driven processes
affecting the liver.
DE Acquired Immunodeficiency Syndrome/MICROBIOLOGY *Herpesviridae
Infections *Herpesvirus 4, Human Hodgkin's Disease/MICROBIOLOGY Human
Infectious Mononucleosis/MICROBIOLOGY Liver/*MICROBIOLOGY Liver
Diseases/*MICROBIOLOGY Lymphoma, Non-Hodgkin's/MICROBIOLOGY
Lymphoproliferative Disorders/MICROBIOLOGY *Tumor Virus Infections
JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).